Ohsawa et al. 2007
A landmark mechanism paper, often cited when molecular hydrogen is discussed. It is useful background but not a product claim.
Research library
Molecular hydrogen research: studies, reviews and what they show.
The scientific literature on molecular hydrogen is growing. We summarize it carefully: what was studied, what the studies found and what cannot be concluded from them.
Clinical reviews
Reviews summarize human research, administration routes and safety questions across the field.
Inhalation studies
Some studies use inhalation protocols. Their findings cannot be transferred directly to Lita Air.
Exercise literature
Reviews discuss markers of antioxidant capacity. The evidence is mixed and still developing.
Important: this research describes molecular hydrogen as a subject of scientific study. It is not a claim about the I regenerate device or a promise of any specific outcome for an individual user.
Reading list
Research belongs in context.
We use the studies to explain molecular hydrogen as a field, not to promise how any individual will feel.
Publications
Selected reading on molecular hydrogen.
The links go to PubMed. These studies describe molecular hydrogen as a field of research. They are not claims about Lita Air or about how any individual will experience the device. The evidence is promising but not yet sufficient for general clinical recommendations.
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
The foundational study reporting that hydrogen selectively reduces the most cytotoxic oxygen radical without quenching radicals that have a physiological role.
Oxidative Stress and Pathways of Molecular Hydrogen Effects in Medicine
A review of the molecular pathways through which hydrogen is thought to influence oxidative stress, and of its proposed applications.
Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis
A review of how hydrogen is proposed to regulate oxidative stress, inflammation and apoptosis (programmed cell death).
Molecular Hydrogen Therapy — A Review on Clinical Studies and Outcomes
A review of 81 clinical trials and human studies, covering administration methods and their safety challenges.
Molecular hydrogen therapy for neurological diseases: a review of current evidence
A review of current evidence for hydrogen in neurological conditions.
Convenient methods for ingestion of molecular hydrogen: drinking, injection, and inhalation
Describes three practical ways to administer hydrogen (drinking, injection and inhalation) and gives an overview of methods and safety.
Efficacy of inhaled hydrogen on neurological outcome following brain ischaemia (HYBRID II)
A multicenter randomized trial of inhaled hydrogen in post-cardiac-arrest care.
A double-blinded, randomized controlled clinical trial of hydrogen inhalation therapy for idiopathic sudden sensorineural hearing loss
A double-blind, randomized controlled trial of hydrogen inhalation for sudden sensorineural hearing loss.
Can molecular hydrogen supplementation reduce exercise-induced oxidative stress in healthy adults? A systematic review and meta-analysis
A systematic review and meta-analysis of hydrogen and exercise-induced oxidative stress in healthy adults.
Drinking or inhaling
Research on hydrogen-rich water.
Molecular hydrogen is not only studied through inhalation. In some studies, participants drink hydrogen-rich water instead. The two routes give different exposure, so findings from one cannot be transferred to the other. For hydrogen water as well, the evidence is promising but not yet sufficient for health claims. Read our hydrogen water guide.
Educational guides
Guides that put the research in context.
Hydrogen inhalation
Inhaler vs water
Titanium PEM
Safety
Next step
Decide in your own time.
Buy Lita Air with a 30-day return window, or book a trial session at our clinic in Stockholm first. If you buy within 60 days, the session fee is credited in full.